Background: Third molar extraction is one of the most common oral and maxillofacial surgeries. Impaction happens when teeth don't erupt in time. This produces dental arch space and too much soft tissue, a hereditary disease that affects eruption, the length of the dental arch, the amount of space available for emerging teeth, and the placement and size of neighboring teeth may all cause tooth impaction. The aim of this study is to facilitating the difficulties of extraction and bleedings.

Martial and Methods: Case control study of impacted tooth used an adipose cell for injection in the sites of impacted tooth of case group. The case groups injected with adipose cells while the control didn’t inject with any cells. Tomography, difficulty of extraction and bleeding tests used for evaluation before and after intervention.

Results: Bleeding degrees in control group were highest than in case groups with significant differences (p. value 0.05). Difficulty of extraction in both groups evaluated and resulted in high levels at the extraction of control group while it was low in case group.

Conclusion: This novel study concluded that the injection of adipose cells under and around impacted tooth led to make the extraction more facilitated and decreasing the bleeding. The formation of adipose tissue after 2 weeks of transplantation reduces the pressure of extraction on the soft tissue of moth and gingiva.